I’m ready to find relief

Includes medication & delivery

Mental Health Support

Treatment & medication
for anxiety relief online

Get affordable and accessible
psychiatric care from anywhere.
Access social and performance anxiety treatments including
prescription medications 100% online and take control of
constant worry, fear, or even panic.
GET STARTED

Includes medication & delivery

Providers online & available

4.9
7,900 REVIEWS

On Apple App Store and Google Play

LifeMD+

4:30pm

Your prescription is filled at the LifeMD
pharmacy and will be shipped today.

LifeMD+

9:45pm

Hi. Just checking in to see how
you’re feeling. We’re here for you!

Prescribed Online

Escitalopram

Lexapro®

DELIVERED
  • Board-Certified Providers

  • 50 States Served

  • 745,000 Patients

  • 100% Online Virtual Care

  • 4.9 Star App Rating

  • 4.9 Star Google Play

Connect with licensed experts - anytime, anywhere

Clinically proven psychiatry treatments

LifeMD offers comprehensive, personalized anxiety
care. Our secure virtual platform makes
accessing
quality mental health care easy.

  • General anxiety
    treatment online

    Get general treatment from home

    Get Started
  • Performance anxiety
    treatment online

    Treatment when you need it

    Get Started
  • Social anxiety
    treatment online

    Ongoing treatment & relief

    Get Started

Daily or as-needed treatments

Get prescription medications
online through LifeMD

Important safety information

Begin your evaluation now. Find out if clinically trusted anxiety treatments could be a
good fit for you. All treatments and medications are tailored to symptom severity and
lifestyle needs.

Start free assessment
  • Wellbutrin SR®

    Bupropion SR
    • 150MG
    • Tablet
    • Generic available
    Get Started
  • Lexapro®

    Escitalopram
    • 10MG
    • Tablet
    • Generic available
    Get Started
  • Prozac®

    Fluoxetine
    • 10MG-20MG
    • Capsule
    • Generic available
    Get Started
  • Inderal®

    Propranolol
    • 40MG
    • Tablet
    • Generic available
    Get Started
  • Buspar

    Buspirone HCI
    • 15MG
    • Tablet
    • Generic available
    Get Started
  • Celexa®

    Citalopram
    • 20MG
    • Tablet
    • Generic available
    Get Started
  • Cymbalta®

    Duloxetine
    • 30MG
    • Capsule
    • Generic available
    Get Started
  • Effexor®

    Venlafaxine
    • 37.5MG-75MG
    • Tablet
    • Generic available
    Get Started
  • Zoloft®

    Sertraline
    • 50MG-100MG
    • Tablet
    • Generic available
    Get Started
  • Paxil®

    Paroxetine
    • 20MG
    • Tablet
    • Generic available
    Get Started

What to expect

Anxiety treatment online
in just
3 easy steps.

Start by answering some simple questions about how you are feeling.
This will help your provider determine the best path forward.

  • Step-1: Start your consultation

    Answer a few questions about what you’re
    experiencing and connect with a
    licensed
    provider to discuss treatment options.

  • Step-2: Receive a diagnosis

    Your provider will evaluate symptoms
    and if appropriate, provide personalized
    treatment options.

  • Step-3: Begin a treatment plan

    Your provider will create a personalized
    plan which may include prescription
    medication and ongoing support.

Starting treatment is “no big deal” through LifeMD.

GET STARTED

Providers online & available

Mental Health
Do any of these factors or
events play a role in how you
are feeling?
Anxious in social settings
Depressed about going to work
Anxious during meetings
Generally feeling anxious
None of the above
Results
Your mental health score

You're one step closer to understanding how
you're feeling—and we're here to guide you
toward the care you deserve.

Mild anxiety

8 / 30
What this might feel like
  • Feeling anxious or on edge
  • Thoughts that won’t stop
  • Worrying more than usual

Mild depression

8 / 30
What this might feel like
  • Little interest in doing things
  • Feeling low or withdrawn
  • Sleeping more than usual
Medication

We've got a simple solution that may help.

Based on your responses, we recommend starting with Escitalopram, a well-tolerated, daily treatment for mood and anxiety relief.

$99
Escitalopram

Escitalopram is typically taken once a day and is known to provide steady support for anxiety and depression over time.

What's included:

  • Single-dose pills, renews every month

  • $99 (includes medication and delivery)

Treating anxiety is no big deal through LifeMD.

GET STARTED

Providers online & available

Treatment & Support

We make it easier to navigate daily
life and emotional challenges.

Anxiety medications can play a key role in reducing
symptoms, improving emotional balance, and
helping you feel more like yourself.

Accessible and affordable

Access mental health
treatments
that fit your
budget.

Affordable mental health care is within reach. The LifeMD Mental Health
Program offers options to help get you treatment that’s right for you.

Social & Performance Anxiety:

Designed for situational anxiety (such as public speaking or social events). It includes an initial
review of your health information and secure messaging with your provider, ongoing message-
based support, and a set amount of medication each month if prescribed.

Anxiety & Depression:

Ideal for managing ongoing anxiety or depression. This Daily Treatment Plan includes an initial
video visit with a provider, the option for ongoing support through secure messaging, and
includes a 30-day supply of medication if prescribed.

GET STARTED

Providers online & available

  • Zoloft®

    Prescribed

    Sertraline
  • Inderal®

    Prescribed

    Propranolol
  • Paxil®

    Prescribed

    Paroxetine
  • Zoloft®

    Prescribed

    Sertraline
  • Inderal®

    Prescribed

    Propranolol
  • Paxil®

    Prescribed

    Paroxetine
It’s never been simpler

Fast track your relief.

“If you’re feeling anxious or depressed,
getting prescription medication isn’t as
difficult as you might think.”

Social & Performance Anxiety:

Designed for situational anxiety (such as public speaking or social events). It includes an initial review of your health information and secure messaging with your provider, ongoing message-based support, and a set amount of medication each month if prescribed.

Anxiety & Depression:

Ideal for managing ongoing anxiety or depression. This Daily Treatment Plan includes an initial video visit with a provider, the option for ongoing support through secure messaging, and includes a 30-day supply of medication if prescribed.

We’re here to provide the care and support
that are
right for your individual needs.

GET STARTED

Providers online & available

Connect with a mental
health provider today

Get started with effective, affordable online treatment
for anxiety and feel more like yourself again. Take the first step and
connect to a licensed prescriber.

GET STARTED
LifeMD+

4:30pm

Please feel free to reach out anytime if
you have questions.

Frequently Asked Questions

Get trust-worthy answers through LifeMD

LifeMD+

9:45pm

Please feel free to reach out anytime if
you have questions.

  • What is anxiety?

    Anxiety is a common condition marked by persistent nervousness, worry, or fear that can interfere with daily life.

  • How do I know if I have anxiety?

    You may have anxiety If you often feel tense, avoid certain situations, or experience racing thoughts or physical symptoms.

  • What's the difference between performance and social anxiety?

    Performance anxiety occurs before events like public speaking; social anxiety involves fear of being judged in social settings.

  • What treatment options are available?

    Treatment options typically include medication management and provider support, depending on your condition and care plan.

  • How does LifeMD treat anxiety?

    LifeMD treats anxiety through personalized medication plans and ongoing virtual consultations with licensed providers.

  • What medications may be prescribed?

    The medication prescribed will depend on your symptoms and goals. SSRIs may be prescribed to treat anxiety. Alternatively, beta blocker medications are sometimes prescribed "off-label" to treat anxiety.

  • Will I need to take medication every day?

    Some patients may only need medication before specific events. Others may benefit from daily treatment.

  • How long does it take to feel results?

    Results will always vary. For performance or social anxiety, medications are usually taken as needed and may begin working within an hour.

  • What can I expect after starting treatment?

    Many patients feel more in control, less tense, and more capable in high-stress moments after starting care.

  • How often do I meet with my provider?

    You'll check in monthly, and you can message your provider anytime through the patient portal. Depending on your situation, you or your provider may request an additional video visit.

  • What if I have questions between appointments?

    You can securely message your provider anytime through the patient portal with questions or concerns.

  • How do refills work?

    You’ll complete a short set of renewal questions to help your provider assess whether your medication is working effectively, monitor for side effects, and make any needed adjustments.

  • Will my dosage change over time?

    It depends. Your provider may adjust your dosage based on monthly check-ins and symptom tracking.

  • Is everything handled online?

    Yes. All care, from consultations to prescription delivery, is handled online for convenience, privacy, and flexibility.

We’re here for your well-being.

Expert treatment to support all
mental health needs.

  • Depression

    Depression is a lasting mood disorder that can cause sadness, low energy, and loss of interest. It typically lasts at least two weeks and can interfere with daily life. If untreated, it can impact your daily life, relationships, and overall well-being.

    Start free assessment
  • Insomnia

    Insomnia involves difficulty falling asleep, staying asleep, or
    waking too early. LifeMD providers treat both short-term
    insomnia—lasting days or weeks—and chronic insomnia that
    persists for three months or longer.

    Start free assessment
  • PTSD

    Following a traumatic event, it’s common to experience mood
    changes, trouble concentrating, or disturbing flashbacks.
    These symptoms can begin to disrupt your daily life. The good
    news: treatment is available and can make a real difference.

    Start free assessment
  • General Anxiety

    Anxiety can show up as constant worry, fear, or even panic. It’s
    common for these feelings to be paired with symptoms like
    muscle tension or shortness of breath. These symptoms can
    make it hard to focus, stay social, or manage everyday tasks.

    Start free assessment

Connect with licensed experts - anytime, anywhere

Clinically proven psychiatry treatments

LifeMD offers comprehensive, personalized care through licensed professionals and medication.
Our secure virtual platform makes accessing quality mental health care “no big deal”.

GET STARTED

Includes medication & delivery

Providers online & available

Important Notice: Talk to your psychiatrist or healthcare professional about the possible risks and benefits associated with the above medications
before starting treatment. LifeMD does not offer therapy or counseling services and is not equipped to respond to mental health emergencies. If you’re
experiencing a crisis, please call 911 or visit the nearest emergency room. IF YOU ARE CONTEMPLATING SUICIDE, CONTACT 911 OR CALL/TEXT THE
NATIONAL SUICIDE PREVENTION LINE AT 988.
These services are available 24/7.

Find treatment and relief
for anxiety

When you need medication for your
mental health, there’s no time to wait!

Important Safety Information

Last Updated: June 28, 2025

Table of Contents

  1. Ramelteon
  2. Trazodone
  3. Doxepin


 

Call your doctor if your insomnia worsens or is not better within 7 to 10 days. This may mean that there is another condition causing your sleep problem.

Be sure that you are able to devote 7 to 8 hours to sleep before being active again. Never take this medicine during your normal waking hours, unless you have at least 7 to 8 hours to dedicate to sleeping.

Ramelteon should be taken within 30 minutes of bedtime. Do not take with alcohol or with other medicines that can make you sleepy. You should not drive or operate machinery at night after taking Ramelteon. Until you know how you will react to Ramelteon, you should be careful in performing such activities during the day following taking Ramelteon. Before you take Ramelteon, tell your doctor if you have a history of depression, mental illness or suicidal thoughts. You should call your doctor right away if after taking Ramelteon you walk, drive, eat or engage in other activities while asleep. Drowsiness is the most common adverse event observed in clinical trials. For more information, please see the complete Prescribing Information, including the Medication Guide.

What should I tell my healthcare provider before taking Ramelteon?

Before you take Ramelteon, tell your healthcare provider if you:

  • Have a history of depression, mental illness, or suicidal thoughts
  • Have severe sleep apnea
  • Have kidney or liver problems
  • Have a history of drug or alcohol abuse or addiction
  • Have a history of glaucoma or urinary retention
  • Have any other medical conditions

Tell your doctor about all of the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements.

Ramelteon and other medicines may affect each other causing side effects. Ramelteon may affect the way other medicines work, and other medicines may affects how Ramelteon works. Especially tell your healthcare provider if you take: Luvox (fluvoxamine).

Who should not take Ramelteon?

You should not use Ramelteon if you are allergic to it, or if:

  • You have severe liver disease; or
  • You also take fluvoxamine.

Ask your doctor or pharmacist if you are not sure if your medicine is one that is listed above.

Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.

Do not use Ramelteon for a condition for which it was not prescribed. Do not share Ramelteon with other people, even if you think they have the same symptoms that you have. It may harm them.

INDICATIONS

Ramelteon is a sedative, also called a hypnotic. It works by affecting certain substances in your body that help regulate your "sleep-wake cycle."

Ramelteon is used to treat insomnia that is associated with having trouble falling asleep.

Dosing In Adults

The recommended dose of Ramelteon is 8 mg taken within 30 minutes of going to bed. It is recommended that Ramelteon not be taken with or immediately after a high-fat meal. The total Ramelteon dose should not exceed 8 mg per day.

Dosing In The Elderly

The recommended starting dose of Ramelteon in elderly patients (≥ 65 years old) is 8 mg once daily.

Administration

Ramelteon should be taken within 30 minutes of bedtime.

To minimize the potential for next day effects, Ramelteon should not be taken within 3 hours of a meal.

The total Ramelteon dose should not exceed 8 mg per day.

How should I take Ramelteon?

  • Take Ramelteon exactly as your healthcare provider tells you to take it.
  • Your healthcare provider will tell you how much Ramelteon to take and when to take them.
  • Your healthcare provider may change your dose if needed.
  • Take Ramelteon within 30 minutes of bedtime. After taking Ramelteon, you should confine your activities to those necessary to prepare for bed.
  • Do not take Ramelteon within 3 hours of a meal. Ramelteon may not work as well, or may make you sleepy the next day if taken with or right after a meal.
  • Do not take Ramelteon unless you are able to get a full night of sleep before you must be active again.

Call your healthcare provider if your sleep problems get worse or do not get better within 7 to 10 days. This may mean that there is another condition causing your sleep problem.

If you take too much Ramelteon, call your doctor or get medical help right away.

What should I avoid while taking Ramelteon?

You should not drink alcohol while taking Ramelteon. Alcohol can increase your chances of getting serious side effects with Ramelteon. You should not drive, operate heavy machinery, or do other dangerous activities after Ramelteon. You may still feel drowsy the next day after taking Ramelteon. Do not drive or do other dangerous activities after taking Ramelteon until you feel fully awake.

What is the most important information I should know about Ramelteon?

The most common side effect of Ramelteon is drowsiness or tiredness.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Ramelteon. For more information ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

How should I store Ramelteon?

Store Ramelteon between 68° and 77°F (20° to 25°C).

Keep Ramelteon in a tightly closed container, and away from light. Safely throw away medicine that is out of date or no longer needed.

Keep Ramelteon and all medicines out of the reach of children.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Read the Medication Guide that comes with trazodone hydrochloride tablets before you start taking it and each time you get a refill. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or treatment. Talk to your healthcare provider or pharmacist if there is something you do not understand or you want to learn about trazodone hydrochloride tablets.

What is the most important information I should know about trazodone hydrochloride tablets?

Antidepressant medicines, depression or other serious mental illnesses, and suicidal thoughts or actions: Talk to your healthcare provider about:

  • All risks and benefits of treatment with antidepressant medicines
  • All treatment choices for depression or other serious mental illnesses

1. Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment.

2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a higher risk of having suicidal thoughts or actions. These include people who have or have a family history of bipolar illness (also called manic- depressive illness) or suicidal thoughts or actions.

3. How can I watch for and try to prevent suicidal thoughts and actions?

  • Pay close attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts or feelings. Keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you are worried about symptoms.
  • Call a healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:
    • Thoughts about suicide or dying
    • Attempts to commit suicide
    • New or worse depression
    • New or worse anxiety
    • Feeling very agitated or restless
    • Panic attacks
    • Trouble sleeping (insomnia)
    • New or worse irritability
    • Acting aggressive, being angry or violent
    • Acting on dangerous impulses
    • An extreme increase in activity and talking (mania)
    • Other unusual changes in behavior or mood

4. Visual problems:eye pain changes in vision swelling or redness in or around the eye

  • eye pain
  • changes in vision
  • swelling or redness in or around the eye

Only some people are at risk for these problems. You may want to undergo an eye examination to see if you are at risk and receive preventative treatment if you are.

5. What else do I need to know about antidepressant medicines?

Never stop an antidepressant medicine without first talking to a healthcare provider.

Stopping an antidepressant medicine suddenly can cause other symptoms.

Antidepressants are medicines used to treat depression and other illnesses. It is important to discuss all the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider, not just the use of antidepressants.

Antidepressant medicines have other side effects. Talk to your healthcare provider about the side effects of your medicines.

Antidepressant medicines can interact with other medicines. Know all of the medicines that you take. Keep a list of all medicines to show your healthcare provider. Do not start new medicines without first checking with your healthcare provider.

Trazodone hydrochloride tablets are not approved for use in children. Talk to your healthcare provider for more information

What are trazodone hydrochloride tablets?

Trazodone hydrochloride tablets are a prescription medicine used to treat major depressive disorder in adults.

What should I tell my healthcare provider before taking trazodone hydrochloride tablets?

Before you take trazodone hydrochloride tablets tell your healthcare provider if you:

  • have heart problems, including QT prolongation or a family history of it
  • have ever had a heart attack
  • have bipolar disorder
  • have liver or kidney problems
  • have other serious medical conditions
  • are pregnant or plan to become pregnant. Trazodone hydrochloride tablets may harm your unborn baby. Talk to your healthcare provider if you are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if trazodone hydrochloride tablets into your breast milk. You and your healthcare provider should decide if you will take trazodone hydrochloride or breastfeed.
  • have taken a Monoamine Oxidase Inhibitor (MAOI) or if you have stopped taking an MAOI in the last 2 weeks.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Using trazodone hydrochloride tablets with certain other medicines can affect each other causing serious side effects.

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

How should I take trazodone hydrochloride tablets?

  • Take trazodone hydrochloride tablets exactly as your healthcare provider tells you.
  • If you feel drowsy after taking trazodone hydrochloride tablets, talk to your healthcare provider. Your healthcare provider may change your dose or the time of day you take your trazodone hydrochloride tablets.
  • Do not stop taking trazodone hydrochloride tablets without talking to your healthcare provider.
  • Trazodone hydrochloride tablets should be swallowed whole or broken in half along the score line. Do not chew or crush trazodone hydrochloride tablets. Tell your healthcare provider if you cannot swallow trazodone either whole or as a half tablet. If you take too much trazodone hydrochloride, call your doctor or go to the nearest emergency room right away.

What should I avoid while taking trazodone hydrochloride tablets?

  • Do not drive, operate heavy machinery, or do other dangerous activities until you know how trazodone hydrochloride tablets affect you. Trazodone hydrochloride tablets can slow your thinking and motor skills.
  • Do not drink alcohol or take other medicines that make you sleepy or dizzy while taking trazodone hydrochloride tablets until you talk with your healthcare provider. Trazodone hydrochloride tablets may make your sleepiness or dizziness worse if you take it with alcohol or other medicines that cause sleepiness or dizziness.

What are the possible side effects of trazodone hydrochloride tablets?

Trazodone hydrochloride tablets can cause serious side effects or death. See “What is the most important information I should know about trazodone hydrochloride tablets?”

Serious side effects include:

  • Serotonin syndrome. Symptoms of serotonin syndrome include: agitation, hallucinations, problems with coordination, fast heartbeat, tight muscles, trouble walking, nausea, vomiting, diarrhea.
  • Feeling high or in a very good mood, then becoming irritable, or having too much energy, feeling like you have to keep talking or do not sleep (mania).
  • Irregular or fast heartbeat or faint (QT prolongation).
  • Low blood pressure. You feel dizzy or faint when you change positions (go from sitting to standing).
  • Unusual bruising or bleeding.
  • Erection lasting for more than 6 hours (priapism).
  • Low sodium in your blood (hyponatremia). Symptoms of hyponatremia include: headache, feeling weak, feeling confused, trouble concentrating, memory problems and feeling unsteady when you walk.
  • Withdrawal symptoms. Symptoms of withdrawal can include anxiety, agitation, and sleep problems. Do not stop taking trazodone hydrochloride tablets without talking to your healthcare provider.

Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of trazodone hydrochloride tablets include:

  • Sleepiness
  • Dizziness
  • Constipation
  • Blurry vision

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of trazodone hydrochloride tablets. For more information, ask your healthcare provider or pharmacist .

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

 

Call your doctor if your insomnia worsens or is not better within 7 to 10 days. This may mean that there is another condition causing your sleep problem.

Be sure that you are able to devote 7 to 8 hours to sleep before being active again. Doxepin should be taken within 30 minutes of bedtime. Do not take with alcohol or with other medicines that can make you sleepy. If you are on a monoamine oxidase inhibitor (MAOI) or have taken a MAOI within the past two weeks, you should not take Doxepin. You should not take Doxepin if you have an eye problem called narrow angle glaucoma that is not being treated, if you have severe urinary retention, or if you are allergic to any of the ingredients in Doxepin. You should not drive or operate machinery at night after taking Doxepin. Until you know how you will react to Doxepin, you should be careful in performing such activities during the day following taking Doxepin. Before you take Doxepin, tell your doctor if you have a history of depression, mental illness or suicidal thoughts. You should call your doctor right away if after taking Doxepin you walk, drive, eat or engage in other activities while asleep. Drowsiness is the most common adverse event observed in clinical trials. For more information, please see the complete Prescribing Information, including the Medication Guide.

It is not known if Doxepin is safe and effective in children.

What should I tell my healthcare provider before taking Doxepin?
Before you take Doxepin, tell your healthcare provider if you:

  • See “Who should not take Doxepin?”
  • Have a history of depression, mental illness, or suicidal thoughts
  • Have severe sleep apnea
  • Have kidney or liver problems
  • Have a history of drug or alcohol abuse or addiction
  • Have a history of glaucoma or urinary retention
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. It is not known if Doxepin will harm your unborn baby.
  • Talk to your healthcare provider if you are pregnant or plan to become pregnant.
  • Are breast-feeding or plan to breast-feed. Doxepin can pass into your milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take Doxepin.
  • You should not breast-feed while taking Doxepin.
  • Tell your doctor about all of the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements.

Doxepin and other medicines may affect each other causing side effects. Doxepin may affect the way other medicines work, and other medicines may affects how Doxepin works. Especially tell your healthcare provider if you take:

  • A monoamine oxidase inhibitor (MAOI).

Who should not take Doxepin?
You should not take Doxepin if you take:

  • Cimetidine (Tagamet) or other medicines that can affect certain liver enzymes.
  • Certain allergy medicines (antihistamines) or other medicines that can make you sleepy or affect your breathing.
  • The diabetes medicine tolazamide.
  • Ask your doctor or pharmacist if you are not sure if your medicine is one that is listed above.

Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide.

Do not use Doxepin for a condition for which it was not prescribed. Do not share Doxepin with other people, even if you think they have the same symptoms that you have. It may harm them.

INDICATIONS

SILENOR® is indicated for the treatment of insomnia characterized by difficulty with sleep maintenance. The clinical trials performed in support of efficacy were up to 3 months in duration.

DOSAGE AND ADMINISTRATION

The dose of SILENOR® should be individualized.

Dosing In Adults

The recommended dose of SILENOR® for adults is 6 mg once daily. A 3 mg once daily dose may be appropriate for some patients, if clinically indicated.

Dosing In The Elderly

The recommended starting dose of SILENOR® in elderly patients (≥ 65 years old) is 3 mg once daily. The daily dose can be increased to 6 mg, if clinically indicated.

Administration

SILENOR® should be taken within 30 minutes of bedtime.

To minimize the potential for next day effects, SILENOR® should not be taken within 3 hours of a meal.

The total SILENOR® dose should not exceed 6 mg per day.

How should I take Doxepin?

  • Take Doxepin exactly as your healthcare provider tells you to take it.
  • Your healthcare provider will tell you how many Doxepin to take and when to take them.
  • Your healthcare provider may change your dose if needed.
  • Take Doxepin within 30 minutes of bedtime. After taking Doxepin, you should confine your activities to those necessary to prepare for bed.
  • Do not take Doxepin within 3 hours of a meal. Doxepin may not work as well, or may make you sleepy the next day if taken with or right after a meal.
  • Do not take Doxepin unless you are able to get a full night of sleep before you must be active again.
  • Call your healthcare provider if your sleep problems get worse or do not get better within 7 to 10 days. This may mean that there is another condition causing your sleep problem.
  • If you take too much Doxepin, call your healthcare provider or get medical help right away.

What should I avoid while taking Doxepin?

  • You should not drink alcohol while taking Doxepin. Alcohol can increase your chances of getting serious side effects with Doxepin.
  • You should not drive, operate heavy machinery, or do other dangerous activities after Doxepin.
  • You may still feel drowsy the next day after taking Doxepin. Do not drive or do other dangerous activities after taking Doxepin until you feel fully awake.

What is the most important information I should know about Doxepin?

  • The most common side effect of Doxepin is drowsiness or tiredness.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Doxepin. For more information ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

How should I store Doxepin?

  • Store Doxepin between 68° and 77°F (20° to 25°C).
  • Keep Doxepin in a tightly closed container, and away from light. Safely throw away medicine that is out of date or no longer needed.
  • Keep Doxepin and all medicines out of the reach of children.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.