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Omeprazole is a medication that treats GERD symptoms, Zollinger-Ellison syndrome, and esophageal damage in adults and children. It is available as both an over-the-counter (OTC) and prescription medication.
It’s sold over the counter (OTC) under the brand name Prilosec to treat heartburn. It’s available as a delayed-release tablet, delayed-release packet, and granules.
Omeprazole works by reducing high amounts of stomach acid that may lead to heartburn and injury to the esophagus.
You may qualify for omeprazole if you have GERD, Zollinger-Ellison syndrome, and frequent heartburn.
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A healthcare provider can help you determine the appropriate dosage of omeprazole you should take. Generally, a healthcare provider may recommend around 20 to 80 mg (milligrams), depending on the condition being treated.
Health experts do not recommend taking more than one dose within a 24 hour period. If you miss a dose, skip it and continue with your regular dosing schedule.
Omeprazole is a short-term medication. Be sure to discuss how long you should take the medication with your healthcare provider. Prescription omeprazole may be prescribed for longer than OTC omeprazole (Prilosec).
A healthcare provider may not recommend omeprazole if you have a history of the following health conditions:
Omeprazole may worsen symptoms for those who have trouble swallowing food or have consistently experienced bloody or black stools.
As with any medication, it’s possible to be allergic to omeprazole. Be sure to let a licensed healthcare provider know if you experience an allergic reaction while taking omeprazole.
No, omeprazole is not a controlled substance.
Be sure to let your healthcare provider know if you are pregnant or thinking about becoming pregnant before starting omeprazole. A healthcare provider can determine whether omeprazole is safe for you to take during pregnancy.
Generally, health experts do not recommend drinking alcohol while taking omeprazole.
While it’s rare, some may experience weight gain while taking omeprazole.
It takes omeprazole one to four days to begin working in your system.
Highly acidic foods may irritate the stomach lining while taking omeprazole.
The following common side effects may occur while taking omeprazole:
Some people may experience severe side effects while taking omeprazole, like:
As with any medication, it’s possible to experience an allergic reaction to omeprazole. Be sure to let a healthcare provider know if you start to experience allergic reactions while taking omeprazole.
Omeprazole may interact with certain blood thinners, prescription antifungals, anxiety medication, and prescription heart medication.
It’s possible to overdose on omeprazole. Be sure to seek emergency assistance right away if you begin to experience signs of an overdose.
Yes! With LifeMD, you can connect with a licensed healthcare provider from the comfort of your home within an hour. If appropriate, your provider may prescribe omeprazole and send it directly to your local pharmacy.
For even more flexibility, a LifeMD+ membership gives you 24/7 access to care, same-day prescription refills, exclusive wellness perks, and easy access to lab testing — all designed to make managing your health simple and stress-free.
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