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Diclofenac sodium is an NSAID (nonsteroidal anti-inflammatory drug) used to treat pain and reduce inflammation. Diclofenac sodium is the active ingredient in the brand name medication Voltaren.
Voltaren is a topical gel version of diclofenac sodium that reduces the effects of enzymes like COX-1 and COX-2 to reduce inflammation. It’s typically used to treat arthritis pain and inflammation. Voltaren is a gel that can be applied to the skin three to four times daily around the knee, ankle, feet, or hands. Diclofenac sodium is available as a topical cream, gel, or tablet.
Diclofenac sodium works by blocking enzymes in the body that increase inflammation. The reduction in inflammatory enzymes reduces pain.
A healthcare provider will evaluate you to determine your eligibility for diclofenac sodium. They will review your medical history, health status, and other factors. Diclofenac sodium is commonly prescribed to treat the following conditions:
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Common side effects of diclofenac sodium include:
It’s important to know that not everyone will experience the same side effects while using diclofenac sodium. If you experience these or any additional symptoms, reach out to a healthcare provider.
Diclofenac sodium is not a controlled substance.
Consider limiting your alcohol intake while using diclofenac sodium. Drinking while using the medication may increase your risk of adverse side effects.
Severe side effects of Voltaren include:
Be sure to reach out to a healthcare provider if you experience severe side effects. Other side effects that may require immediate medical attention include a loss of appetite, unusual bleeding, and a fever.
Voltaren is one of the topical gel brand name versions of diclofenac sodium. However, diclofenac sodium is also available as a generic cream for arthritis pain or as a tablet.
Diclofenac sodium is stronger than ibuprofen. It takes smaller doses of diclofenac sodium to have the same effects as ibuprofen.
Be sure to follow directions from a licensed healthcare provider on the proper dosage to apply. Using more than four doses of Voltaren can lead to adverse side effects.
Diclofenac can have effects in the body within the first four hours. Diclofenac sodium may stay in the body for up to three weeks.
Generally, diclofenac sodium is not recommended during pregnancy. Be sure to talk to your LifeMD-affiliated healthcare provider before using diclofenac sodium while pregnant.
The following medications may interact with diclofenac sodium:
Be careful not to apply sunscreen or other cosmetic lotions and moisturizers to the area where you apply diclofenac sodium gel. It’s recommended to avoid extended exposure to real or artificial sunlight.
Diclofenac sodium is not recommended for long-term use unless approved by your healthcare provider.
You can apply the next dose as soon as you remember. However, if it’s close to the time of your next scheduled dose, you can skip the missed dose and continue with your regular schedule. Do not apply more than four doses of Voltaren in a day. Be sure to listen to a healthcare provider's directions on how to properly apply Voltaren.
Yes! With LifeMD, you can connect with a licensed healthcare provider from the comfort of your home within an hour. If appropriate, your provider may prescribe diclofenac sodium and send it directly to your local pharmacy.
For even more flexibility, a LifeMD+ membership gives you 24/7 access to care, same-day prescription refills, exclusive wellness perks, and easy access to lab testing — all designed to make managing your health simple and stress-free.
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