Get Prescription Isosorbide Mononitrate Online

Isosorbide mononitrate may be right for you if you have frequent, ongoing chest pain (angina) due to heart disease and need a long-acting medication to prevent it. It’s typically prescribed when other treatments aren’t enough on their own or if your symptoms are predictable and triggered by activity or stress.

A healthcare provider can determine if it’s appropriate based on your symptoms, heart health, blood pressure, and any other medications you're taking.

Isosorbide mononitrate does not directly affect your heart rate, but it can sometimes cause a reflex increase in heart rate (called reflex tachycardia).

This happens because the drug lowers blood pressure by relaxing blood vessels. In response, your body may try to compensate by speeding up the heart rate. For most people, this effect is mild or doesn't happen at all.

If you notice a racing heart or feel lightheaded while taking isosorbide mononitrate, it’s a good idea to let your healthcare provider know – they may adjust your dose or review other medications you're taking.

Yes, isosorbide mononitrate lowers blood pressure by relaxing and widening your blood vessels. This makes it easier for blood to flow and reduces the amount of work your heart has to do.

While this effect helps prevent chest pain (angina), it can sometimes cause low blood pressure symptoms like:

• Dizziness
• Lightheadedness
• Fainting, especially when standing up quickly

If you experience these symptoms, especially when starting the medication or changing your dose, let your healthcare provider know.

No, isosorbide mononitrate does not help with erectile dysfunction (ED) – and in fact, it can be dangerous to use it with ED medications.

Isosorbide mononitrate is a nitrate used to treat chest pain from heart disease, and it works by relaxing blood vessels. ED medications like sildenafil (Viagra), tadalafil (Cialis), and others also relax blood vessels – but combining the two can cause a dangerous drop in blood pressure, which can lead to fainting, heart attack, or stroke.

If you have ED and are taking isosorbide mononitrate, talk to your provider. They can help you find safe treatment options that won’t put your heart health at risk.

Ibuprofen (and other NSAIDs) can sometimes interfere with heart medications, raise blood pressure, and increase the risk of cardiovascular events like heart attack or stroke, particularly with long-term use. Since isosorbide mononitrate is prescribed to reduce heart strain and manage chest pain, combining it with ibuprofen could potentially reduce its effectiveness or introduce added risk.

Always check with your healthcare provider before using ibuprofen regularly while on isosorbide mononitrate. In some cases, acetaminophen (Tylenol) may be a safer option for managing pain.

The most common side effects of isosorbide mononitrate are usually mild and may include:

• Headache (very common, especially when starting treatment)
• Dizziness or lightheadedness
• Flushing (warmth or redness in the face or neck)
• Low blood pressure
• Fatigue
• Nausea

If side effects persist or become severe – especially if you feel faint, have chest pain, or experience vision changes – contact your healthcare provider immediately.

Yes! With LifeMD, you can connect with a licensed healthcare provider from the comfort of your home within an hour. If appropriate, your provider may prescribe isosorbide mononitrate and send it directly to your local pharmacy.

For even more flexibility, a LifeMD+ membership gives you 24/7 access to care, same-day prescription refills, exclusive wellness perks, and easy access to lab testing — all designed to make managing your health simple and stress-free.

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